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  • CSB Student Profile: Clay Tydings

    CSB Student Profile: Clay Tydings

    Clay Tydings, Walker and Meiler Labs Teamwork makes the dream work! Clay Tydings, of the Walker and Meiler Labs, thinks collaboration is key to not only furthering his scientific endeavors but also for achieving a personal goal. Meet Clay … What… Read More

    Feb. 7, 2025

  • Investigations into inositol phosphates: the mTOR regulators you鈥檝e never heard of!

    Investigations into inositol phosphates: the mTOR regulators you鈥檝e never heard of!

    Ray Blind, Medicine Inositol phosphates are a family of small metabolites characterized by their different phosphorylation patterns. Inositol hexakisphosphate (IP6), the fully phosphorylated form of inositol phosphate, is found in many organisms and is the most abundant inositol phosphate in animal and plant cells. IP6 serves a wide range of… Read More

    Jan. 31, 2025

  • Jenny Tran wins the Dr. Anne Karpay Award in Structural Biology

    Jenny Tran wins the Dr. Anne Karpay Award in Structural Biology

    Congratulations to Jenny Tran, of the Breann Brown lab, on being named the 2025 recipient of the Dr. Anne Karpay Award in Structural Biology. 鈥淚t鈥檚 such an honor to be selected as the recipient of the Karpay Award,鈥 Tran said. Although she completed a summer… Read More

    Jan. 23, 2025

  • Jenny Tran presents Karpay Award Seminar January 21

    Jenny Tran presents Karpay Award Seminar January 21

    2025 Anne Karpay Award in Structural Biology Winner Jenny Tran, of the Breann Brown lab, gives the MBTP/CSB Seminar on Tuesday, January 21, at 12:20pm in 1220 MRB3. Although in high school Jenny completed a summer research internship with Howard Hughes Medical Institute Professor David… Read More

    Jan. 17, 2025

  • CSB Research Faculty Profile: Heather Kroh

    CSB Research Faculty Profile: Heather Kroh

    Heather Kroh, PhD, Pathology, Microbiology and Immunology Heather Kroh, PhD, is a research assistant professor in the Pathology, Microbiology and Immunology department and currently works in the Lacy lab. With a long-standing dedication to scientific education, she participates in many mentoring and outreach programs,… Read More

    Jan. 9, 2025

  • A preprocessing package tailored to individual needs

    A preprocessing package tailored to individual needs

    Will Wan, Biochemistry Cryo-electron tomography (cryo-ET) is method for determining structure that relies on tilting a microscope sample stage to collect a wide range of sample views. This unique acquisition technique is especially useful for imaging in the context of cells or intact extracellular particles, allowing researchers to study structure… Read More

    Jan. 3, 2025

  • Unmasking antagonists: a deep dive into the structural binding poses of PPAR纬 ligands

    Unmasking antagonists: a deep dive into the structural binding poses of PPAR纬 ligands

    Doug Kojetin, Biochemistry Peroxisome proliferator-activated receptor 纬 (PPAR纬) is a ligand-regulated transcription factor located in the nucleus. Endogenous ligands, such as lipids and fatty acids, bind an orthosteric pocket in the ligand-binding domain (LBD) of PPAR纬 and function as agonists to activate gene expression related to adipogenesis and insulin sensitization. Read More

    Dec. 13, 2024

  • CSB Research Spotlight: Mchaourab Lab – Describing聽 conformational landscapes of cell membrane transporters

    CSB Research Spotlight: Mchaourab Lab – Describing聽 conformational landscapes of cell membrane transporters

    PhD student Alexandra Schwartz and Professor Hassane Mchaourab (Molecular Physiology and Biophysics, Center for Applied Artificial Intelligence in Protein Dynamics) developed a methodological blueprint to describe the structure of cell membrane transporters. Read more to learn how the Spectroscopy and AI method provide a unique window… Read More

    Dec. 6, 2024

  • CSB Research Spotlight: Ren Lab – Understanding mRNA export

    CSB Research Spotlight: Ren Lab – Understanding mRNA export

    A newly determined structure from the lab of Yi Ren reveals information about the mRNA export pathway and suggests that herpes viruses could hijack that interaction to infect their host. The new structures also reveal how certain mutations in the protein complex could play a role in cancers. First… Read More

    Dec. 5, 2024

  • Looking in All Directions: Exploring a New Horizon for PCOS Therapeutics

    Looking in All Directions: Exploring a New Horizon for PCOS Therapeutics

    Kathryn R. Brewer, Sanders Lab This article was originally published in The Protein Society’s November 2024 Under the Microscope newsletter. It is published here by permission of The Protein Society and the author. By Kathryn R. Brewer, PhD Candidate in Biochemistry, Sanders Lab A 20-year-old woman waits… Read More

    Nov. 14, 2024