  {"id":5143,"date":"2024-02-21T08:19:06","date_gmt":"2024-02-21T14:19:06","guid":{"rendered":"https:\/\/www.vanderbilt.edu\/csb\/?p=5143"},"modified":"2024-02-21T08:19:06","modified_gmt":"2024-02-21T14:19:06","slug":"csb-core-update","status":"publish","type":"post","link":"https:\/\/www.vanderbilt.edu\/csb\/2024\/02\/21\/csb-core-update\/","title":{"rendered":"CSB Core Update"},"content":{"rendered":"<p><img data-attachment-id=\"5146\" data-permalink=\"https:\/\/www.vanderbilt.edu\/csb\/2024\/02\/21\/csb-core-update\/coreupdategraphic\/\" data-orig-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic.png\" data-orig-size=\"1640,924\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"CoreUpdateGraphic\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic-300x169.png\" data-large-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic-1024x577.png\" loading=\"lazy\" class=\"alignleft wp-image-5146 size-medium\" src=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic-300x169.png\" alt=\"\" width=\"300\" height=\"169\" srcset=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic-300x169.png 300w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic-1024x577.png 1024w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic-768x433.png 768w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic-1536x865.png 1536w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21081220\/CoreUpdateGraphic.png 1640w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>The Biophysical Instrumentation Core and the Megalab Core have been combined to form the new <strong><em>ÌÇÐÄVlog¹Ù·½ Center for Structural Biology Labs and Instrumentation Facility<\/em><\/strong>.<\/p>\n<p>The facility supports mass photometry, biolayer interferometry, stopped-flow spectrometry, microscale thermophoresis, dynamic light scattering, circular dichroism and microcalorimetry instruments for measuring macromolecular conformation, stability and binding interactions. The facility also provides expression vectors\/strains and technical expertise to assist researchers with large-scale production of recombinant proteins in <em>E. coli<\/em>.<a href=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing.png\"><img data-attachment-id=\"5145\" data-permalink=\"https:\/\/www.vanderbilt.edu\/csb\/2024\/02\/21\/csb-core-update\/csb-biophysical-core_feb2024-pricing\/\" data-orig-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing.png\" data-orig-size=\"951,535\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"CSB-Biophysical-Core_Feb2024-pricing\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing-300x169.png\" data-large-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing.png\" loading=\"lazy\" class=\"alignright wp-image-5145\" src=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing.png\" alt=\"\" width=\"520\" height=\"293\" srcset=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing.png 951w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing-300x169.png 300w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080725\/CSB-Biophysical-Core_Feb2024-pricing-768x432.png 768w\" sizes=\"(max-width: 520px) 100vw, 520px\" \/><\/a><\/p>\n<p>With the new name comes updated usage rates. The various instruments are separated into a tiered pricing structure. Click on the image to the right to see the rates.<\/p>\n<p><img data-attachment-id=\"5144\" data-permalink=\"https:\/\/www.vanderbilt.edu\/csb\/2024\/02\/21\/csb-core-update\/saracho-kroh-3\/\" data-orig-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080630\/Saracho-Kroh-3.png\" data-orig-size=\"329,748\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"Saracho-Kroh-3\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080630\/Saracho-Kroh-3-132x300.png\" data-large-file=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080630\/Saracho-Kroh-3.png\" loading=\"lazy\" class=\"alignleft wp-image-5144\" src=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080630\/Saracho-Kroh-3.png\" alt=\"\" width=\"100\" height=\"227\" srcset=\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080630\/Saracho-Kroh-3.png 329w, https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/212\/2024\/02\/21080630\/Saracho-Kroh-3-132x300.png 132w\" sizes=\"(max-width: 100px) 100vw, 100px\" \/>VU and VUMC researchers receive one-on-one instrument training so that they will be able to perform their experiments independently. <a href=\"mailto:noah.saracho@vanderbilt.edu\">Email Noah Saracho<\/a> to set up core access and to schedule training. <a href=\"mailto:heather.k.kroh@vumc.org\">Email Facility Director Heather Kroh<\/a> to schedule a consultation to discuss experimental strategies or to provide advice on specific research projects.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Biophysical Instrumentation Core and the Megalab Core have been combined to form the new ÌÇÐÄVlog¹Ù·½ Center for Structural Biology Labs and Instrumentation Facility. The facility supports mass photometry, biolayer interferometry, stopped-flow spectrometry, microscale thermophoresis, dynamic light scattering, circular dichroism and microcalorimetry instruments for measuring macromolecular conformation, stability and binding interactions. The facility also provides&#8230;<\/p>\n","protected":false},"author":1185,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"spay_email":"","jetpack_publicize_message":"","jetpack_is_tweetstorm":false,"jetpack_publicize_feature_enabled":true},"categories":[1],"tags":[],"acf":[],"jetpack_featured_media_url":"","jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/posts\/5143"}],"collection":[{"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/users\/1185"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/comments?post=5143"}],"version-history":[{"count":12,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/posts\/5143\/revisions"}],"predecessor-version":[{"id":5158,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/posts\/5143\/revisions\/5158"}],"wp:attachment":[{"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/media?parent=5143"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/categories?post=5143"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/csb\/wp-json\/wp\/v2\/tags?post=5143"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}