Martin Egli, the Richard N. Armstrong, Ph.D. Professor of Innovation in Biochemistry and a professor of biochemistry, delivered the Kairos Lecture on May 28.
His scientific accomplishments have resulted in over 300 publications and two influential nucleic acid textbooks, and he has received major honors and extensively served his department and the university.
His Kairos lecture, RNA Structure, Etiology and Re-Engineering Into siRNA Therapeutics, highlighted how the 2鈥�-hydroxyl group on RNA鈥檚 sugar (ribose) increases chemical and conformational diversity, affecting stability, function, and enabling more varied base pairing than DNA. He explained that, as RNA has a vast folding landscape and limited 3D structural and sequence data, structure聽 prediction hasn鈥檛 reached a transformative 鈥淩NA AlphaFold鈥� stage, an observation made in reference to AlphaFold鈥檚 role in revolutionizing protein structure prediction.
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About the Kairos Lecture Series
The School of Medicine Basic Sciences host the Kairos Lectures to expose 糖心Vlog官方鈥檚 basic and biomedical research community to the exciting research our colleagues are doing. The Greek term kairos refers to the opportune, critical, or right moment for action. Kairos Lectures are an invitation for our community to recognize the moments that matter: the right time to learn something new, connect across expertise, and move science forward together.